Gene Detail

Gene Symbol PKN1
Synonyms DBK | PAK-1 | PAK1 | PKN | PKN-ALPHA | PRK1 | PRKCL1
Gene Description PKN1, protein kinase N1, is a member of the protein kinase C superfamily that mediates Rho-dependent signaling pathways, thus regulates cell migration, invasion, and gene expression (PMID: 25504435, PMID: 28222172). Increased Pkn1 expression has been identified in glioma, kidney, ovarian, and prostate cancer, and pancreatic ductal adenocarcinoma (PMID: 30206226).
Entrez Id 5585
Chromosome 19
Map Location 19p13.12
Canonical Transcript NM_002741

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