Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol PRKDC
Synonyms DNA-PKC | DNA-PKcs | DNAPK | DNAPKc | DNPK1 | HYRC | HYRC1 | IMD26 | p350 | XRCC7
Gene Description PRKDC, protein kinase, DNA-activated, catalytic polypeptide, is the catalytic component of the DNA-PK complex, which functions in DNA repair by non-homologous end-joining (PMID: 14726021, PMID: 24680878). PRKDC overexpression has been demonstrated in colorectal and prostate cancers (PMID: 26992638, PMID: 27856181).


Additional content available in CKB BOOST