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|Synonyms||ERK | ERK-2 | ERK2 | ERT1 | MAPK2 | p38 | p40 | p41 | p41mapk | p42-MAPK | P42MAPK | PRKM1 | PRKM2|
|Gene Description||MAPK1, mitogen-activated protein kinase 1, translocates to the nucleus upon activation by upstream kinases, thereby influencing many cellular processes, including cell proliferation (PMID: 22450690). Dysregulation of MAPK1 is associated with several human tumor types (PMID: 12937136) and altered regulation of Mapk1 by a number of long coding RNAs (PMID: 32293550, PMID: 31819520), circular RNAs (PMID: 32110054), and micro-RNAs (PMID: 32266816, PMID: 31939714, PMID: 31564913), has been frequently observed in various cancers.|