Gene Detail

Gene Symbol MAPK3
Synonyms ERK-1 | ERK1 | ERT2 | HS44KDAP | HUMKER1A | p44-ERK1 | p44-MAPK | P44ERK1 | P44MAPK | PRKM3
Gene Description MAPK3, mitogen-activated protein kinase 3, is a serine/threonine kinase involved in the MAPK pathway, thus, playing a role in cellular processes including proliferation, survival, migration, differentiation, and transcription (PMID: 22569528). A few MAPK3 mutations have been demonstrated to confer resistance to ERK inhibitors in vitro (PMID: 25320010).
Entrez Id 5595
Chromosome 16
Map Location 16p11.2
Canonical Transcript NM_002746


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