Gene Detail

Gene Symbol PRLR
Synonyms HPRL | hPRLrI | MFAB | RI-PRLR
Gene Description PRLR, prolactin receptor, is a member of the type 1 cytokine receptor superfamily that binds the hormone, prolactin, to activate Jak2/Stat5, MAPK, and PI3K pathways for control of lactation (PMID: 28377489, PMID: 27107001). Overexpression of PRLR has been observed in multiple subtypes of breast cancer (PMID: 28377489).
Entrez Id 5618
Chromosome 5
Map Location 5p13.2
Canonical Transcript NM_000949


Additional content available in CKB BOOST