Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol GRIPAP1
Synonyms GRASP-1
Gene Description GRIPAP1, GRIP1-associated protein 1, is a neuron-specific endosome protein that promotes endosome maturation recycling and regulates synaptic transmission and plasticity through AMPA receptor trafficking, and acts as a scaffold protein in the JNK signaling pathway (PMID: 28285821, PMID: 15897011, PMID: 17761173). A GRIPAP1-NTRK1 fusion has been identified in lung adenocarcinoma (PMID: 28235761).
Additional content available in CKB BOOST