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Gene Symbol GRIPAP1
Synonyms GRASP-1
Gene Description GRIPAP1, GRIP1-associated protein 1, is a neuron-specific endosome protein that promotes endosome maturation recycling and regulates synaptic transmission and plasticity through AMPA receptor trafficking, and acts as a scaffold protein in the JNK signaling pathway (PMID: 28285821, PMID: 15897011, PMID: 17761173). A fusion of GRIPAP1 with NTRK1 has been observed in lung adenocarcinoma (PMID: 28235761).


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