Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol ESYT2
Synonyms CHR2SYT | E-Syt2 | FAM62B
Gene Description ESYT2, extended synaptotagmin 2, is a calcium-binding protein (PMID: 17360437, PMID: 24373768) that plays a role in interaction between the plasma membrane and endoplasmic reticulum (PMID: 23791178, PMID: 27044890), and may function in regulating growth factor signaling (PMID: 20833364, PMID: 23213466). An ESTY2-BRAF fusion has been identified in lung cancer (PMID: 36153311).
Additional content available in CKB BOOST