Gene Detail

Gene Symbol BARD1
Gene Description BARD1, BRCA1 associated RING domain 1, forms a heterodimer with Brca1 resulting in protein stabilization and thereby mediating Brca1 tumor suppression (PMID: 8944023). Germline mutations in BARD1 are associated with increased susceptibility to breast and ovarian cancers (PMID: 21344236) and somatic mutations are highest in colon and endometrial cancers (PMID: 27283171).
Entrez Id 580
Chromosome 2
Map Location 2q35
Canonical Transcript NM_000465

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