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|Synonyms||PTPSIGMA | R-PTP-S | R-PTP-sigma|
|Gene Description||PTPRS, protein tyrosine phosphatase receptor type S, plays a role in regulation of intestinal epithelial permeability (PMID: 24385580) and autophagy (PMID: 21303930), and has a putative role in regulation of RAS signaling (PMID: 29915291). PTPRS mutations have been identified in colorectal cancer (PMID: 29915291), and deletion of PTPRS has been identified in head and neck cancers (PMID: 22065749).|