Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : firstname.lastname@example.org
|Synonyms||HPTPZ | HPTPzeta | phosphacan | PTP-ZETA | PTP18 | PTPRZ | PTPZ | R-PTP-zeta-2 | RPTPB | RPTPbeta|
|Gene Description||PTPRZ1, protein tyrosine phosphatase, receptor type Z1, encodes for a receptor that is activated by Hif2a and is involved in signal transduction and primarily expressed during central nervous system development (PMID: 20224786). PTPRZ1-MET fusions have been observed in glioma (PMID: 30343896) and overexpression of PTPRZ1 has been seen in a variety of tumors, including glioblastoma, renal carcinoma, and hepatocarcinoma (PMID: 20224786).|