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Gene Symbol NECTIN2
Synonyms CD112 | HVEB | PRR2 | PVRL2 | PVRR2
Gene Description NECTIN2, nectin cell adhesion molecule 2, is a member of the immunoglobulin superfamily that mediates formation of cell adhesion through homotypic and heterotypic interactions, and plays a role in regulating transendothelial migration of immune cells and differentiation of sperm cells (PMID: 25733141, PMID: 24116228). Expression of Nectin2 has been identified in acute myeloid leukemia (PMID: 29855615), and overexpression in breast and ovarian cancer (PMID: 23758976).

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