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Gene Symbol NECTIN2
Synonyms CD112 | HVEB | PRR2 | PVRL2 | PVRR2
Gene Description NECTIN2, nectin cell adhesion molecule 2, is a member of the immunoglobulin superfamily that plays a role in cell-cell adhesion, regulation of transendothelial migration of immune cells (PMID: 25733141, PMID: 24116228), and in negative regulation of CD8-positive T-cell function (PMID: 30659054). Increased Nectin2 expression has been identified in several tumor types (PMID: 30659054), including breast and ovarian cancer (PMID: 23758976).
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