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Gene Symbol ARHGAP22
Synonyms RhoGAP2 | RhoGap22
Gene Description ARHGAP22, Rho GTPase activating protein 22, is a GTPase-activating protein involved in regulation of the actin cytoskeleton (PMID: 24933155), and cell motility (PMID: 21969604). Increased ARHGAP22 promoter methylation has been identified in melanoma (PMID: 31602702) and FGFR2-ARHGAP22 has been identified in cholangiocarcinoma (PMID: 33218975).
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