Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@jax.org
| Gene Symbol | RRAGD | ||||||||||
| Synonyms | bA11D8.2.1 | HOMG7 | RAGD | ||||||||||
| Gene Description | RRAGD, Ras related GTP binding D, encodes a GTPase that forms a heterodimer with RRAGA or RRAGB (PMID: 18497260), which interacts with the Ragulator complex to regulate amino acid-dependent lysosomal targeting and activation of mTORC1 (PMID: 20381137, PMID: 18497260). Increased RRAGD expression has been observed in squamous cell lung carcinomas (PMID: 23226795). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
