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|Synonyms||BROVCA3 | FANCO | R51H3 | RAD51L2|
|Gene Description||RAD51C, RAD51 paralog C, functions in homologous recombination in DNA repair and plays a role in cell cycle checkpoint signaling in response to DNA damage (PMID: 21821141). Germline mutations in RAD51C are associated with increased susceptibility to breast and ovarian cancers (PMID: 21821141, PMID: 31446535) and overexpression of RAD51C has been observed in ovarian cancer (PMID: 32055267).|