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Gene Symbol KDM5A
Synonyms RBBP-2 | RBBP2 | RBP2
Gene Description KDM5A, lysine demethylase 5A, is a Jumonji domain histone demethylase, transcriptional repressor, and epigenetic modifier (PMID: 29602065), that regulates gene transcription through chromatin remodeling to promote cell growth and differentiation (PMID: 30650517). KDM5A overexpression has been reported in a number of cancers including breast cancer (PMID: 22937203) and decreased expression may be prognostic for glioma (PMID: 29324315).
Additional content available in CKB BOOST