Gene Detail
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| Gene Symbol | KDM5A | ||||||||||
| Synonyms | RBBP-2 | RBBP2 | RBP2 | ||||||||||
| Gene Description | KDM5A, lysine demethylase 5A, is a Jumonji domain histone demethylase, transcriptional repressor, and epigenetic modifier (PMID: 29602065), that regulates gene transcription through chromatin remodeling to promote cell growth and differentiation (PMID: 30650517). KDM5A overexpression has been reported in a number of cancers including breast cancer (PMID: 22937203) and decreased expression may be prognostic for glioma (PMID: 29324315). | ||||||||||
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