Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol CCND1
Synonyms BCL1 | D11S287E | PRAD1 | U21B31
Gene Description CCND1, G1/S-specific cyclin-D1, interacts with CDK4 and CDK6 to regulate the cell-cycle in transition from G1 to S phase (PMID: 28611330, PMID: 27695879). Amplification and/or overexpression of CCND1 has been associated with many tumor types, including breast, lung, liver, colorectal cancer, and mantle cell lymphoma (PMID: 28611330), where overexpression of Ccnd1 may promote tumorigenesis (PMID: 19917254).


Additional content available in CKB BOOST