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Gene Symbol RFC5
Synonyms RFC36
Gene Description RFC5, replication factor C subunit 5, encodes the 36-kDa subunit of the replication factor C complex, which loads PCNA onto DNA (PMID: 9488738, PMID: 34751190), and is involved in DNA replication (PMID: 8692942, PMID: 10656791, PMID: 10656792) and maintenance of genomic stability (PMID: 33339954). Increased RFC5 expression has been demonstrated in HPV-positive head and neck squamous cell carcinoma (PMID: 17079134) and lung cancer (PMID: 30214556).
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