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Gene Symbol ACTB
Synonyms BRWS1 | PS1TP5BP1
Gene Description ACTB, actin beta, encodes a cytoskeletal protein that plays a role in regulating cellular pools of globular actin (PMID: 21900491), gene expression (PMID: 20053683), chromatin remodeling (PMID: 30557298, PMID: 22573825), and cell growth and migration (PMID: 21900491). Increased ACTB expression has been identified in gastric cancer (PMID: 23635433), and a fusion with FOSB has been observed in pseudomyogenic hemangioendothelioma (PMID: 30459475), and with GLI1 in pericytomas (PMID: 15111311, PMID: 15555571).


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