Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol AFAP1
Synonyms AFAP | AFAP-110 | AFAP110
Gene Description AFAP1, actin filament associated protein 1, binds actin and regulates actin filament organization, plays a role in SRC activation, and may function as an adaptor protein for signaling molecules (PMID: 11607843, PMID: 21236256, PMID: 25043309). AFAP1 over expression has been demonstrated in prostate cancer (PMID: 17885682), and a fusion between AFAP1 and NTRK2 has been demonstrated in low-grade glioma (PMID: 25204415).


Additional content available in CKB BOOST