Gene Detail

Gene Symbol BCL6
Synonyms BCL5 | BCL6A | LAZ3 | ZBTB27 | ZNF51
Gene Description BCL6, B-cell CLL/lymphoma 6, functions as a transcriptional repressor in germinal center B cells, playing a role in B-lymphocyte development, and is critical for cell survival and proliferation (PMID: 20498019). Increased expression of BCL6 has been associated with both solid and hematological malignancies including DLBCL, neuroblastoma, and breast cancer (PMID: 24917186).
Entrez Id 604
Chromosome 3
Map Location 3q27.3
Canonical Transcript NM_001706


Additional content available in CKB BOOST