Gene Detail


Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at :

Gene Symbol BCR
Synonyms ALL | BCR1 | CML | D22S11 | D22S662 | PHL
Gene Description BCR, BCR activator of RhoGEF and GTPase, is a serine-threonine protein kinase, which may be involved in cell regulation and signaling (PMID: 15494376). Fusion proteins of BCR-ABL1 result in constitutive kinase activity and have been reported in various cancers (PMID: 18851712) and BCR-ABL1 is also known as the Philadelphia chromosome and is prevalent in chronic myeloid leukemia (PMID: 18827185, PMID: 21435002).
Additional content available in CKB BOOST