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| Gene Symbol | RPS6KA3 | ||||||||||
| Synonyms | CLS | HU-3 | ISPK-1 | MAPKAPK1B | MRX19 | p90-RSK2 | pp90RSK2 | RSK | RSK2 | S6K-alpha3 | XLID19 | ||||||||||
| Gene Description | RPS6KA3, ribosomal protein S6 kinase A3, is also referred to as RSK2 and is a serine/threonine kinase that acts downstream of the RAS/MAPK pathway and plays a role in regulation of cell cycle progression (PMID: 24086335, PMID: 27491410, PMID: 36566564), DNA repair and genomic stability (PMID: 24086335), and neuronal development and function (PMID: 16217014, PMID: 17663748, PMID: 19555761). RPS6KA3 mutations are recurrent in hepatocellular carcinoma (PMID: 22561517, PMID: 37201672). | ||||||||||
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