Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@jax.org
| Gene Symbol | SALL2 | ||||||||||
| Synonyms | COLB | HSAL2 | p150(Sal2) | Sal-2 | ZNF795 | ||||||||||
| Gene Description | SALL2, Sal-like protein 2, is a member of the spalt-like (SALL) transcription factor family that regulates a number of gene targets, including TP53, CDKN1A, and MYC and may play a role as a tumor suppressor or oncogene, depending on context (PMID: 28430874, PMID: 27957650). Altered Sall2 expression has been observed in several tumor types, including serous ovarian carcinoma and glioblastoma (PMID: 27957650), and a SALL2-BRAF fusion has been reported in NSCLC (PMID: 29883838). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
