Gene Detail
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| Gene Symbol | SDC4 | ||||||||||
| Synonyms | SYND4 | ||||||||||
| Gene Description | SDC4, syndecan 4, is a heparan sulfate proteoglycan that plays a role in intracellular signaling, including cell adhesion and cell-matrix interactions (PMID: 23844358). SDC4 expression has been associated with breast cancer, a SDC4-ROS1 fusion has been identified in NSCLC (PMID: 25361632, PMID: 22919003), and a SDC4-NRG1 fusion has been identified in lung adenocarcinoma and squamous cell carcinoma (PMID: 29610121, PMID: 28950338, PMID: 25531467). | ||||||||||
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