Gene Detail


Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at :

Gene Symbol SDC4
Synonyms SYND4
Gene Description SDC4, syndecan 4, is a heparan sulfate proteoglycan that plays a role in intracellular signaling, including cell adhesion and cell-matrix interactions (PMID: 23844358). SDC4 expression has been associated with breast cancer, a SDC4-ROS1 fusion has been identified in NSCLC (PMID: 25361632, PMID: 22919003), and a SDC4-NRG1 fusion has been identified in lung adenocarcinoma and squamous cell carcinoma (PMID: 29610121, PMID: 28950338, PMID: 25531467).
Additional content available in CKB BOOST