Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol PRDM1
Synonyms BLIMP1 | PRDI-BF1
Gene Description PRDM1, PR/SET domain 1, encodes a repressor of beta-interferon gene expression (PMID: 1851123) and regulates plasma cell differentiation (PMID: 27687004). PRDM1 plays a tumor suppressor role in various tumor types (PMID: 22143801; PMID: 20047096) and decreased expression may predict poor survival in colon cancer patients (PMID: 29760071) and may promote metastasis in lung cancer (PMID: 28378641).


Additional content available in CKB BOOST