Gene Detail

Gene Symbol SDHB
Synonyms CWS2 | IP | PGL4 | SDH | SDH1 | SDH2 | SDHIP
Gene Description SDHB, succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial, is the iron-sulfur catalytic subunit in mitochondrial complex II that catalyzes electron transfer from succinate to ubiquinone (PMID: 21771581). SDHB mutations are frequently found in pheochromocytomas, aggressive extra-adrenal paragangliomas (PMID: 23457139, PMID: 21771581), and pituitary carcinomas (PMID: 28284009).
Entrez Id 6390
Chromosome 1
Map Location 1p36.13
Canonical Transcript NM_003000


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