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| Gene Symbol | SDHB | ||||||||||
| Synonyms | CWS2 | IP | MC2DN4 | PGL4 | PPGL4 | SDH | SDH1 | SDH2 | SDHIP | ||||||||||
| Gene Description | SDHB, succinate dehydrogenase complex iron sulfur subunit B, is the iron-sulfur catalytic subunit in mitochondrial complex II that catalyzes electron transfer from succinate to ubiquinone (PMID: 21771581). SDHB mutations are frequently found in pheochromocytomas, aggressive extra-adrenal paragangliomas (PMID: 23457139, PMID: 21771581), and pituitary carcinomas (PMID: 28284009). | ||||||||||
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