Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : email@example.com
|Synonyms||CYB560 | CYBL | PGL3 | QPS1 | SDH3|
|Gene Description||SDHC, succinate dehydrogenase cytochrome b560 subunit, mitochondrial, is the large membrane-bound subunit of cytochrome b in mitochondrial complex II that catalyzes electron transfer from succinate to ubiquinone (PMID: 21771581). SDHC germline mutations are found paragangliomas (PMID: 19454582), pheochromocytomas (PMID: 17557926), adrenocortical carcinomas (PMID: 28819017), and somatic promoter methylation leads to decreased expression of Sdhc in parasympathetic paragangliomas (PMID: 29126304).|