Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : email@example.com
|Synonyms||CRL2 | CRLF2Y | TSLPR|
|Gene Description||CRLF2, cytokine receptor-like factor 2, acts as a cell membrane receptor for thymic stromal lymphopoietin (TSLP), resulting in downstream activation of JAK2, STAT3 and STAT5 pathways (PMID: 22685175). Mutations and rearrangements of Crlf2 are associated with acute lymphoblastic leukemeia (PMID: 22685175, PMID: 31318944, PMID: 30487598).|