Gene Detail
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| Gene Symbol | SLC12A2 | ||||||||||
| Synonyms | BSC | BSC-2 | BSC2 | CCC1 | KILQS | NKCC1 | PPP1R141 | ||||||||||
| Gene Description | SLC12A2, solute carrier family 12 member 2, encodes NKCC1, which is a Na+K+Cl- co-transporter that plays a role epithelial cell function and in regulating cellular homeostasis and volume, and is important for inner ear function (PMID: 24097229, PMID: 25620102). A SLC12A2-INSR fusion has been identified in MSI-high colorectal cancer (PMID: 30279230). | ||||||||||
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