Gene Detail


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Gene Symbol SLCO2A1
Synonyms MATR1 | OATP2A1 | PGT | PHOAD | PHOAR2 | SLC21A2
Gene Description SLCO2A1, solute carrier organic anion transporter family member 2A1, encodes a plasma membrane transporter that mediates the transport of several prostaglandins including prostaglandin E2 and prostaglandin H2 thereby playing a role in autocrine and paracrine signaling and multiple physiological processes (PMID: 25433165, PMID: 20346915, PMID: 25505603). Decreased expression of SLCO2A1 has been observed in colorectal cancer (PMID: 19138942) and an SLCO2A1-ALK fusion has been identified in non-small cell lung cancer (PMID: 32903930).
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