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Gene Symbol SRP54
Synonyms SCN8
Gene Description SRP54, signal recognition particle 54, is part of the ribonucleoprotein complex (PMID: 32277798) that regulates protein shuttling to the ER, and regulates secretion and membrane integration of nascent proteins, including death receptor 4, which mediates apoptosis (PMID: 15356269). Amplification of SRP54 has been identified in esophageal squamous cell carcinoma (PMID: 11550278).
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