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Gene Symbol STAT6
Synonyms D12S1644 | IL-4-STAT | STAT6B | STAT6C
Gene Description STAT6, signal transducer and activator of transcription 6, is a STAT family transcription factor that mediates IL-4/13 signaling and differentiation of Th2 immune cells (PMID: 24470978). Loss of STAT6 in mouse models of colitis-associated colon cancer resulted in reduced tumor formation, inflammation, nuclear beta-catenin, and proliferation in the colon relative to wild-type mice (PMID: 28385737).


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