Gene Detail


Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at :

Gene Symbol KLF5
Synonyms BTEB2 | CKLF | IKLF
Gene Description KLF5, Kruppel-like factor 5, is a transcription factor that activates or represses gene transcription, depending on cellular context, thereby, inhibiting or promoting cell survival (PMID: 24323942). Amplification and overexpression of Klf5 has been observed in a variety of tumor types, including intestinal, bladder, gastric, breast (PMID: 28963353), and pancreatic (PMID: 31327760).
Additional content available in CKB BOOST