Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol TRA
Synonyms IMD7 | TCRA | TRA@
Gene Description TRA, T cell receptor alpha locus, encodes the T-cell receptor alpha chain, which heterodimerizes with T-cell receptor beta chains to form alpha/beta T-cell receptors that are expressed by T-cells and function in recognition of foreign antigens (PMID: 15999096, PMID: 9099797, PMID: 15998791). TRA fusions are associated with T-cell acute lymphoblastic leukemia (PMID: 33467425, PMID: 32150610).
Additional content available in CKB BOOST