Gene Detail


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Gene Symbol THRB
Synonyms C-ERBA-2 | C-ERBA-BETA | ERBA2 | GRTH | NR1A2 | PRTH | THR1 | THRB1 | THRB2 | THRbeta | THRbeta1 | Thrbeta2 | TRb | TRbeta | TRbeta1
Gene Description THRB, thyroid hormone receptor beta, is a nuclear receptor that functions as a transcription factor to mediate thyroid hormone signaling and plays a role in several biological processes including regulation of basal metabolism and growth (PMID: 20051527, PMID: 11427693). THRB mutations have been demonstrated in various tumor types, including hepatorcellular carcinoma (PMID: 22507269), and THRB may play a role in the immune response to lung adenocarcinoma (PMID: 31921619).
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