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Gene Symbol XRCC3
Synonyms CMM6
Gene Description XRCC3, X-ray repair cross complementing 3, is an XRCC gene family member and a RAD51 paralog (PMID: 31275435) that is involved in homologous recombination repair (PMID: 15279796). XRCC3 variants may confer increased cancer risk in a variety of cancers, including breast, skin, lung, and bladder cancers (PMID: 15723711), and hepatocellular carcinoma (PMID: 32281666).


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