Gene Detail


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Gene Symbol XRCC5
Synonyms KARP-1 | KARP1 | KU80 | Ku86 | KUB2 | NFIV
Gene Description XRCC5, X-ray repair cross complementing 5, is an XRCC gene family member that is involved in DNA non-homologous end joining (PMID: 15279796). XRCC5 variants may confer increased cancer risk in breast cancer (PMID: 23098447, PMID: 31920325), and Xrcc5 overexpression has been associated with poor prognosis in hepatocellular carcinoma (PMID: 31599408).
Additional content available in CKB BOOST