Gene Detail

Gene Symbol CXCR4
Synonyms CD184 | D2S201E | FB22 | HM89 | HSY3RR | LAP-3 | LAP3 | LCR1 | LESTR | NPY3R | NPYR | NPYRL | NPYY3R | WHIM | WHIMS
Gene Description CXCR4 (Cd184) chemokine (C-X-C motif) receptor 4, acts as a receptor for both cytokines and ubiquitin, regulating cellular calcium levels and signaling pathways which include PI3K, RAS, and MAPK (PMID: 20228059, PMID: 15339043). CXCR4 expression has been linked to several cancer types and is thought to influence tumor metastasis and vascularization (PMID: 15339043, PMID: 30733896).
Entrez Id 7852
Chromosome 2
Map Location 2q22.1
Canonical Transcript NM_003467

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