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Gene Symbol CAD
Synonyms CDG1Z | EIEE50 | GATD4
Gene Description CAD, carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase, encodes for a protein that is responsible for the biosynthesis of pyrimidines, thus playing a significant role in the process of DNA replication and cell proliferation (PMID: 24332717). A fusion, CAD-ALK, has been observed in colorectal cancer (PMID: 26633560).


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