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Gene Symbol TFEB
Synonyms ALPHATFEB | BHLHE35 | TCFEB
Gene Description TFEB, transcription factor EB, is a transcription factor that regulates lysosomal function and biogenesis, thus involves in cellular response to stress conditions (PMID: 27298091). TFEB fusions have been identified in a subset of renal cell carcinoma (PMID: 27298091) and amplification has also been observed in renal cell carcinoma (PMID: 30269777).


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