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Gene Symbol BIRC7
Synonyms KIAP | LIVIN | ML-IAP | MLIAP | RNF50
Gene Description BIRC7, baculoviral IAP repeat containing 7, is also known as livin and is a member of the inhibitors of apoptosis protein (IAPs) family that regulates apoptosis (PMID: 11084335) and activity of caspases (PMID: 28030838). Overexpression of Birc7 has been observed in melanoma (PMID: 11084335, PMID: 23070005) and papillary thyroid carcinoma (PMID: 32064154), and amplification and overexpression has been reported in prostate cancer (PMID: 30376767).
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