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Gene Symbol RUFY1
Synonyms RABIP4 | ZFYVE12
Gene Description RUFY1, RUN and FYVE domain containing 1, is an effector protein for Rab14 and Rab4, and plays a role in endosomal enlargement and recycling, and interacts with Etk, functioning as a downstream effector (PMID: 20534812, PMID: 11877430). A RUFY1-RET fusion has been identified in MSI-H colorectal cancer (PMID: 30279230).
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