Gene Detail


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Gene Symbol PDCD1LG2
Synonyms B7DC | bA574F11.2 | Btdc | CD273 | PD-L2 | PDCD1L2 | PDL2
Gene Description PDCD1LG2, programmed cell death 1 ligand 2, encodes PD-L2, a ligand for PD-1, which upon interaction exert an inhibitory effect on immune response (PMID: 11224527, PMID: 26432723, PMID: 28018338). PDCD1LG2 (PD-L2) is expressed in several tumor types, and amplification and overexpression of PD-L2, along with PD-L1, has been demonstrated in Hodgkin lymphoma and PMBCL (PMID: 28619999, PMID: 26432723).
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