Gene Detail

Gene Symbol KMT2D
Synonyms AAD10 | ALR | CAGL114 | KABUK1 | KMS | MLL2 | MLL4 | TNRC21
Gene Description KMT2D, histone-lysine N-methyltransferase 2D, is a histone methyltransferase which methylates H3K4me and is involved in transcriptional activation, mostly during development and cell differentiation (PMID: 28669924, PMID: 24240169). KMT2D mutations are associated with various tumor types, including ESCC (PMID: 25151357), follicular lymphoma (PMID: 24362818), and lung (PMID: 28007623, PMID: 27873319).
Entrez Id 8085
Chromosome 12
Map Location 12q13.12
Canonical Transcript NM_003482

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