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Gene Symbol TRIM11
Synonyms BIA1 | RNF92
Gene Description TRIM11, tripartite motif containing 11, is an E3 ubiquitin ligase, which activates the proteasome complex and regulates proteolysis, cell proliferation, migration, invasion, and promotes tumorigenesis (PMID: 29581427, PMID: 28244856, PMID: 27329103, PMID: 23178488). A CRTC1-TRIM11 fusion has been identified in cutaneous melanocytoma (PMID: 29240581).
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