Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : firstname.lastname@example.org
|Synonyms||DXS1272E | JARID1C | MRX13 | MRXJ | MRXSCJ | MRXSJ | SMCX | XE169|
|Gene Description||KDM5C, llysine demethylase 5C, is a histone demethylase, regulating gene transcription through chromatin remodeling to regulate cell growth and differentiation (PMID: 25016185). KDM5C overexpression has been reported in prostate cancer (PMID: 25016185, PMID: 30921702) and mutations have been observed in clear cell renal cell carcinoma and pancreatic cancer (PMID: 31221981).|