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Gene Symbol CDCA7
Synonyms ICF3 | JPO1
Gene Description CDCA7, cell division cycle associated 7, is a member of a chromatin remodeling complex that mediates DNA methylation, chromosome stability (PMID: 33960584, PMID: 33082427, PMID: 31970665, PMID: 30307408), and Myc-dependent transformation (PMID: 23166294, PMID: 15994934). CDCA7 amplification has been identified in esophageal squamous cell carcinoma (PMID: 26833333), increased Cdca7 expression has been reported in gastric carcinoma (PMID: 34082692), endometrial carcinoma (PMID: 32913454), clear cell renal cell carcinoma (PMID: 33648519), lung adenocarcinoma (PMID: 32221746), colorectal cancer (PMID: 32319649), and Burkitt’s lymphoma (PMID: 29880607), and CDCA7-ALK has been identified in lung adenocarcinoma (PMID: 33419583).
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