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Gene Symbol CASP6
Synonyms caspase-6 | CSP-6 | MCH2
Gene Description CASP6, caspase 6, is a cysteine-aspartic acid protease that plays a key role in the process of programmed cell death (PMID: 28726391) and axon degeneration (PMID: 30940883). Overexpression and decreased Casp6 expression have been observed in a variety of tumor types (PMID: 28726391), including gastric cancer (PMID: 31611962), and CASP6 somatic mutations have been identified in gastric and colorectal cancer (PMID: 16948818).
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