Gene Detail
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| Gene Symbol | ABRAXAS1 | ||||||||||
| Synonyms | ABRA1 | CCDC98 | FAM175A | ||||||||||
| Gene Description | ABRAXAS1 (FAM175A), abraxas 1, BRCA1 A complex subunit, is a BRCA1-binding protein that plays a role in DNA repair and regulation of the G2/M cell cycle phase checkpoint (PMID: 17525340, PMID: 29497033). ABRAXAS1 variants have been identified in several breast cancer pedigrees (PMID: 22357538) and contribute to a small proportion of unexplained hereditary breast cancer cases (PMID: 27270457). | ||||||||||
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