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|Synonyms||BFLS | BORJ | CENP-31|
|Gene Description||PHF6, PHD finger protein 6, is involved in chromatin organization, interacts with several factors that regulate transcription, and plays a role in cell-cycle regulation via suppression of ribosomal RNA transcription (PMID: 23229552, PMID: 28607179, PMID: 26103525). PHF6 inactivating mutations have been observed in T-cell acute lymphoblastic leukemia and acute myeloid leukemia (PMID: 20228800, PMID: 21030981, PMID: 26103525) and Phf6 overexpression has been observed in hepatocellular carcinoma (PMID: 30888215).|